Expanded Publication List - Vincenzo Cirulli, MD, PhD

Rouiller D, Cirulli V & Halban PA: “Differences in aggregation properties and levels of the neural cell adhesion molecule (N-CAM) between islet cell types”.  Experimental Cell Research  (1990) 191:305-312.

Giordano E, Bosco D, Cirulli V & Meda P: “Repeated glucose stimulation reveals distinct and lasting secretion patterns of individual rat pancreatic b-cells”. The Journal of Clinical Investigation  (1991) 87:2178-2185.

Rouiller D, Cirulli V & Halban PA: “Uvomorulin mediates Ca++-dependent aggregation of islet cells, whereas Ca++-independent CAMs distinguish between islet cell types”. Developmental Biology  (1991) 148:233-242.

Cirulli V, Halban PA & Rouiller DR: “Tumor necrosis factor-a  modifies adhesion properties of rat islet B-cells”.   The Journal of Clinical Investigation  (1993)  91:1868-1876.

Giordano E, Cirulli V, Bosco D, Rouiller D, Halban PA & Meda P: “B-cell size influences glucose-stimulated insulin secretion”. The American Journal of Physiology (1993) 265, (Cell Physiol. 34):C358-C364).

Chertow BS, Blaner WS, Rajan N, Primerano D, Meda P, Cirulli V, Krozowski Z, Smith R & Cordle MB: “Retinoic acid receptor and cytosolic retinol-binding and retinoic acid-binding protein mRNA transcripts and proteins in rat insulin-secreting cells”.  Diabetes (1993) 42:1109-1114.

Sekine N, Cirulli V, Regazzi R, Brown L, Gine E, Tamarit-Rodriguez J, Girotti M, Marie S, MacDonald MJ, Wollheim CB & Rutter GA: “Glucose metabolism and the control of insulin secretion: low lactate dehydrogenase and high mitocondrial glycerol phosphate dehydrogenase in pancreatic islet B-cells”.   Journal of Biological Chemistry (1994) 269:4895-4902.

Neerman AM, Cirulli V & Halban PA: “Levels of the conversion endoproteases PCI and PC2 distinguish between insulin-producing pancreatic islet b-cells and non-b-cells”. Biochemical  Journal (1994) 300:57-61.

Cirulli V, Baetens D, Rutishauser U, Halban PA, Orci L & Rouiller DR: “Expression of neural cell adhesion molecule (NCAM) and E-cadherin in rat islets and its role in islet cell type segregation”.  Journal of Cell Science (1994) 107:1429-1436.

Hayek A, Beattie G, Cirulli V, Lopez A, Ricordi C & Rubin JS: “Growth factor/matrix-induced proliferation of human adult b-cells”.  Diabetes (1995) 44:458-1460.

Cirulli V, Ricordi C & Hayek A: “E-cadherin, NCAM, and EpCAM expression in human fetal pancreata”.   Transplantation Proceedings  (1995) 27(6):3335.

Levine F, Wang S, Beattie GM, Mally MI, Cirulli V, Lopez AD & Hayek A: “Development of a cell line from the human fetal pancreas”.  Transplantation Proceedings (1995) 27(6):3410.

Mally MI, Cirulli V, Otonkoski T, Soto G & Hayek A: “Ontogeny and tissue distribution of human GAD expression”. Diabetes (1996) 45:496-501.

Mally MI, Cirulli V, Hayek A & Otonkoski T: “ICA69 is equally expressed in the human endocrine and exocrine pancreas”.  Diabetologia  (1996) 39: 474-480.

Crisa L, Cirulli V, Ellisman MH, Ishii JR, Elices MJ & Salomon DR: “Cell adhesion and migration are regulated at distinct stages of thymic T cell development: the roles of fibronectin, VLA4 and VLA5”.   The Journal of Experimental Medicine  (1996) 184: 215-228.

Otonkoski T, Cirulli V, Beattie G, Mally MI, Soto G, Rubin JS & Hayek A: “A role for HGF/SC factor/scatter factor in fetal mesenchyme-induced pancreatic B-cell growth”.  Endocrinology (1996) 137:3131-3139.

Wang S, Beattie GM, Mally M, Cirulli V, Itkin-Ansari P, Lopez AD, Hayek A & Levine F: “Isolation and characterization of a cell line from epithelial cells of the human fetal pancreas”.   Cell Transplantation  (1997) 6: 59-67.

Beattie GM, Crowe JH, Lopez AD, Cirulli V, Ricordi C & Hayek A: “Trehalose: a  cryoprotectant that enhances recovery and preserves function of human pancreatic islets after long-term storage”. Diabetes  (1997) 46: 519-523.

Beattie GM, Cirulli V, Lopez AD & Hayek A: “Ex vivo expansion of human pancreatic endocrine cells”.  The Journal of Clinical Endocrinology and Metabolism  (1997) 82:1852-1856.

Ptasznik A, Beattie GM, Mally MI, Cirulli V, Lopez A & Hayek A: “Phosphatidylinositol 3-kinase is a negative regulator of cellular differentiation”. The Journal of Cell Biology  (1997) 137:1127-1136.

Cirulli V, Crisa L, Beattie GM, Mally MI, Lopez AD, Fannon A, Ptasznik A, Inverardi L, Ricordi C, Deerinck T, Ellisman M, Reisfeld RA & Hayek A: “KSA antigen Ep-CAM mediates cell-cell adhesion of pancreatic epithelial cells: morphoregulatory roles in pancreatic islet development”. The Journal of Cell Biology  (1998) 140:1519-1534.

Beger C, Cirulli V, Vajkoczy P, Halban PA & Menger MD: “Vascularization of purified pancreatic islet-like cell aggregates (pseudoislets) after syngeneic transplantation”. Diabetes  (1998) 47:559-565.

Plopper GE, Domanico S, Cirulli V, Kiosses WB & Quaranta V: “Migration of breast epithelial cells on Laminin-5: differential role of integrins in normal and transformed cell types”.  Breast Cancer Res. Treat. (1998) 51:57-69.

Leibowitz G, Beattie GM, Kafri T, Cirulli V, Lopez AD, Hayek A & Levine F: “Gene transfer to human pancreatic endocrine cells using viral vectors”. Diabetes  (1999) 48:745-753.

Beattie GM, Itkin-Ansari P, Cirulli V, Leibowitz G, Lopez AD, Bossie S, Mally MI, Levine F & Hayek A: “Sustained proliferation of PDX-1+ cells derived from human islets”. Diabetes  (1999) 48:1013-1019.

Crisa L, Cirulli V, Smith KA, Ellisman M, Torbett BE & Salomon DR: “Human Cord blood progenitors sustain thymic T cell development and a novel form of angiogenesis”. Blood (1999) 94:3928-3940. 

Koshikawa N, Giannelli G, Cirulli V, Miyazaki K & Quaranta V: “Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5”. The Journal of Cell Biology (2000) 148:615-624.

Cirulli V, Beattie GM, Klier G, Ellisman M, Ricordi C, Quaranta V, Frasier F, Ishii JK, Hayek A & Salomon DR: “Expression and function of avb3  and avb5  integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells”. The Journal of Cell Biology (2000) 150:1445-1459.

Humphrey RK, Bucay N, Beattie GM, Lopez A, Messam CA, Cirulli V & Hayek A. “Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas.” Diabetes (2003) 52(10):2519-25.

Yebra M, Montgomery AM, Diaferia GR, Kaido T, Silletti S, Perez B, Just ML, Hildbrand S, Hurford R, Florkiewicz E, Tessier-Lavigne M & Cirulli V: “Recognition of the neural chemoattractant Netrin-1 by integrins a6b4 and  a3b1 regulates epithelial cell adhesion and migration”.   Developmental Cell, (2003) 5:695-707.

Kaido T, Perez B, Yebra M, Hill J, Cirulli V, Hayek A & Montgomery AM: “Alpha-v-integrin utilization in human b cell adhesion, spreading and motility”. J. Biol. Chem., (2004) 279(17):17731-7.

Silletti S, Yebra M, Perez B, Cirulli V., McMahon M & Montgomery AM: “Extracellular Signal-regulated Kinase (ERK)-dependent Gene Expression Contributes to L1 Cell Adhesion Molecule-dependent Motility and Invasion”. Journal of Biological Chemistry, (2004), 279(28):28880-28888, (Epub 2004 May 05).

Hildbrand P, Cirulli V, Robyn PC, Smith KA, Torbett BE, Salomon DR & Crisa L: “The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors”. Blood, (2004) 104(7):2010-2019.

Varadi A, Johnson-Cadwell LI, Cirulli V, Yoon Y, Allan VJ & Rutter GA: “Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the dynamin-related protein-1”. Journal of Cell Science, (2004) 117(Pt 19):4389-400.

Kaido T, Yebra M, Cirulli V & Montgomery AM: “Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha1beta1”. Journal of Biological Chemistry, (2004) 279(51):53762-9.

Varadi A, Cirulli V & Rutter GA.  “Mitochondrial localization as a determinant of capacitative Ca2+ entry in HeLa cells”.   Cell Calcium (2004) 36(6):499-508.

Cirulli V, Zalatan J, McMaster M, Prinsen R, Salomon DR, Ricordi C, Torbett BE, Meda P & Crisa L:  “The class I HLA repertoire of pancreatic islets comprises the non-classical class Ib antigen HLA-G.”   Diabetes, (2006) 55(5):1214-22.

Kaido T, Yebra M, Cirulli V, Rhodes CJ, Diaferia G, & Montgomery AM: Impact of Defined Matrix Interactions on Insulin Production by Cultured Human β-cells: Effect on Insulin Content, Secretion, and Gene Transcription.   Diabetes, (2006) 55:2723-9.

Winter M, Cirulli V, Briaire-De Bruijn IH & Litvinov SV: “Cadherins are regulated by Ep-CAM via phosphaditylinositol-3 kinase”.  Mol Cell Biochem. (2007) 302(1-2):19-26. Epub 2007 Feb 14.

Miller R, Cirulli V, Diaferia GR, Ninniri S, Hardiman G Torbett BE, Benezra R, & Crisa L. “Switching-on survival and repair esponse programs by bone marrow-derived vasculogenic cells”   Diabetes, 57(9):2402-2412, 2008.

Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P. “Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.” Hum Mol Genet., 18(3):428-39, 2009.

Bucay N, Yebra M, Cirulli V, Afrikanova I, Kaido T, Hayek A, Montgomery AM. “A novel approach for the derivation of putative primordial germ cells and sertoli cells from human embryonic stem cells.”   Stem Cells, 27(1):68-77, 2009.

Reviews and Book Chapters:
Cirulli V., and Hayek A: "Developmental roles of cell adhesion molecules: Implications for pancreatic islet morphogenesis." Pancreatic Growth and Regeneration, Sarvetnick N., Editor. Austin, TX: RG Landes Press, 1997. (pp. 154-169).

Otonkoski T., Beattie G.M., Cirulli V., Mally M.I. and Hayek A: "Human pancreatic P-cell differentiation and growth in vitro and after transplantation." Pancreatic Growth and Regeneration, Sarvetnick N., Editor. Austin, TX: RG Landes Press, 1997. (pp 231-245).

Serre-Beinier V., Mas C., Calabrese A., Caton D., Bauquis J., Caille D., Charollais A., Cirulli V., and Meda P. "Connexins and secretion". Biology of The Cell, (2002) 94(7-8):477-92.

Cirulli V and Yebra M: “Netrins: beyond the brain”. Nat Rev Mol Cell Biol. (2007) 4:296-306.