The Institute draws upon the expertise of a wide range of investigators with complementary interests in diabetes, obesity, inflammation, lipid metabolism and atherosclerosis. Members of the Institute's faculty conduct both basic research to clarify the mechanisms causing diabetes and obesity and their consequences, and translational research to transform their research findings into clinical solutions.
Two-thirds of the adult U.S. population is overweight and one-half of those individuals – one-third of the adult population – are obese. The prevalence of type 2 diabetes (formerly known as “adult-onset”) has also increased markedly in recent decades not only among adults, but in children as well. Although type 1 diabetes is less common, it is a potentially devastating disorder affecting both children and adults and, while treatments for both types of diabetes exist, neither is curable and effective treatments for obesity have yet to be developed.
Much of the good we accomplish is made possible by private support: by people and organizations underwriting leading-edge research and providing funding to train promising fellows. With your help, the UW Diabetes Institute is improving lives throughout the Northwest and around the world.
Dr. Mauricio Dorfman, PhD, is first author and Dr. Joshua Thaler, MD, PhD is senior author on the article entitled “Sex differences in microglial CX3CR1 signaling determine obesity susceptibility in mice”
Dr. Gregory Morton, PhD, has been awarded a competing renewal for his NIH R01 project entitled “CNS mechanisms governing diabetic hyperglycemia”.
Dr. Francis Kim, MD, has been awarded an NIH R01 grant for his project entitled “Endothelial nitric oxide synthase and regulation of macrophage function”.
Dr. Mauricio Dorfman, PhD, has been awarded an American Heart Association Scientist Development Grant for his project entitled “Sex-specific microglial signaling in the pathogenesis of obesity and diabetes.”
Dr. Michael Schwartz, MD, has been featured by several prominent news organizations in recent weeks to discuss the pathogenesis of obesity in long-term weight loss.
Dr. Jenny Kanter has been awarded an Innovative Basic Science Award from the American Diabetes Association for her project entitled “Diabetes and Myocardial Infarction – Do They Synergize to Accelerate Atherosclerosis?