Jay Heinekce MD - Expanded Publication List

Shao B., Oda M.N., Bergt C., Fu X., Green P.S., Brot N., Oram J.F., Heinecke J.W.: Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I. J. Biol. Chem. 2006;281:9001-4.

Heinecke J.W.: Chemical knock-out of C-reactive protein. Nature Chem. Biol. 2006; 2:300-1, 2006.

Vaisar T., Pennathur S., Green P.S., Gharib S.A., Hoofnagle A.N., Cheung M.C., Byun J., uletic S., Chait A., Zhao X.Q., Elkon K., Marcovina S., Ridker P., Oram J.F., Heinecke J.W.: Shotgun proteomics implicates protease inhibition and complement activation in the anti-inflammatory properties of HDL. J. Clin. Invest. 2007; 117:746-56.

Oram J.F., Heinecke J.W.: When good cholesterol turns bad: the evolving saga of CETP inhibitors and clinical strategies to elevate high-density lipoprotein. Curr. Atheroscler. Rep. 2007;9:425-7

Shao B., Heinecke J.W.: Using MS/MS to quantify site-specific chlorination and nitration of proteins: Model system studies with HDL oxidized by myeloperoxidase. Meth. Enzymol. 2008;440:33-63.

Johansson F., Kramer F., Barnhart S., Kanter J.E., Vaisar T., Merrill R.D., Geng L., Oka K., Chan L., Chait A., Heinecke J.W., Bornfeldt K.E.: Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice. Proc. Natl. Acad. Sci. 2008;105:2082-7.

Kirk E.A., Sagawa Z.K., McDonald T.O., O’Brien K.D., Heinecke J.W.: MCP-1 deficiency fails to restrain macrophage infiltration into adipose tissue. Diabetes. 2008;57:1254-61.

Shao B., Cavigiolio G., Brot N., Oda M.N., Heinecke J.W.: Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I. Proc. Natl. Acad. Sci. 2008;105:12224-9.